10,800 research outputs found

    La ReglamentaciĂłn de los Agrupamientos Caninos de Seguridad PĂşblica y Privada en MĂ©xico.

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    El presente trabajo de tesis contiene tablas comparativas.El presente trabajo busca un fortalecimiento dinámico, eficaz y didáctico en cierto modo, al tomar como uno de los principales elementos en la seguridad tanto pública como privada, un equipo y equipamiento canino, más que compararnos es igualarnos en el nivel de desempeño y desarrollo de una seguridad de alto rendimiento, enfocarnos en los caninos como parte de una eficaz seguridad es por la diversa capacidad de estos en su olfato, lealtad, amor y búsqueda sin distracción del punto neutro

    Neurofuzzy model of an industrial process, reducing complexity by using principal component analysis

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    XVI Congreso Español sobre Tecnologías y Lógica Fuzzy Valladolid, 1-3 de febrero de 2012A Neurofuzzy model of a mixing chamber pressure has been proposed. The process is a part of a copper smelter plant. The principal component analysis (PCA) method has been used to reduce the inputs space for a recurrent fuzzy model. The coupling among variables and their mutual influence between themselves, are taken into account by the projection into the PCA axis. The model have been validated with real data from the factory. The validation result shows that the model is suitable for simulation.Ministerio de Ciencia e Innovación DPI2010-21589-C05-0

    Concurs : una nova etapa

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    PTP1B promotes focal complex maturation, lamellar persistence and directional migration

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    Previous findings established that ER-bound PTP1B targets peripheral cell-matrix adhesions and positively regulates cell adhesion to fibronectin. Here we show that PTP1B enhances focal complex lifetime at the lamellipodium base, delaying their turnover and facilitating α-actinin incorporation. We demonstrate the presence of catalytic PTP1BD181A-α-actinin complexes at focal complexes. Kymograph analysis revealed that PTP1B contributes to lamellar protrusion persistence and directional cell migration. Pull-down and FRET analysis also showed that PTP1B is required for efficient integrin-dependent downregulation of RhoA and upregulation of Rac1 during spreading. A substrate trap strategy revealed that FAK/Src recruitment and Src activity are essential for the generation of PTP1B substrates in adhesions. PTP1B targets the negative regulatory site of Src (phosphotyrosine 529), paxillin and p130Cas at peripheral cell-matrix adhesions. We postulate that PTP1B modulates more than one pathway required for focal complex maturation and membrane protrusion, including α-actinin-mediated cytoskeletal anchorage, integrin-dependent activation of the FAK/Src signaling pathway, and RhoA and Rac1 GTPase activity. By doing so, PTP1B contributes to coordinated adhesion turnover, lamellar stability and directional cell migration.Fil: Burdisso, Juan Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; ArgentinaFil: González, Angela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; ArgentinaFil: Arregui, Carlos Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; Argentin

    Failing and Merging as Competing Alternatives during Times of Financial Distress: Evidence from the Colombian Financial Crisis

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    This paper studies the determinants of individual bank failures and M&A processes in Colombia during the financial crisis of the late 1990s. Using bank-specific data we estimate competing risk hazards models and find that while profitability and capitalization are the most important determinants of the probability of failing, bank´s size, efficiency and capitalization are the main determinants of the probability of participating in an integration process. All else constant, an increase in capitalization reduces the probability of disappearing, whether due to the occurrence of bankruptcy, a merge or an acquisition. However, a marginal increase in capitalization reduces significantly more the probability of bankruptcy than the probability of integration. This study is the first to present a competing risks hazard model to identify covariates that excerpt significant influence on the probability of failing or merging for banks of an emerging economy.Survival analysis; Competing risk models; Colombia. Classification JEL: G21; G33; G33; C25
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